I'm a little late to the party, but msdn has a very good answer to this problem [here][1].



    'Ends Edit Mode So CellValueChanged Event Can Fire
    Private Sub EndEditMode(sender As System.Object, e As EventArgs) _
    	Handles DataGridView1.CurrentCellDirtyStateChanged
    	'if current cell of grid is dirty, commits edit
    	If DataGridView1.IsCurrentCellDirty Then
    		DataGridView1.CommitEdit(DataGridViewDataErrorContexts.Commit)
    	End If
    End Sub

I also wrote up a very detailed elaboration of the msdn fix and those found here on the post [Firing The DataGridView CellValueChanged Event Immediately][2]


  [1]: http://msdn.microsoft.com/en-us/library/system.windows.forms.datagridview.cellcontentclick.aspx
  [2]: http://codingeverything.blogspot.com/2013/01/firing-datagridview-cellvaluechanged.html

DataGridView.CellContentClick is not firing if I mouse click a DataGridViewCheckBoxCell very fast. How can I solve this? I need to know when CheckBox's check state changes

Answer