It's probably easier to leave the listeners attached and then conditionally exit them if the modal is open.
You could setup something like this:
var modalIsOpen = false
$('#myModal').on('shown.bs.modal', function(e) { modalIsOpen = true;})
$('#myModal').on('hidden.bs.modal', function(e) { modalIsOpen = false;})
Then just copy and paste the following line into all of your listeners.
if (modalIsOpen) return;
Demo in Stack Snippets
<!-- begin snippet: js hide: false -->
<!-- language: lang-js -->
var modalIsOpen = false
$('#myModal').on('shown.bs.modal', function(e) { modalIsOpen = true;})
$('#myModal').on('hidden.bs.modal', function(e) { modalIsOpen = false;})
var listener = new window.keypress.Listener();
listener.simple_combo("s", function() {
if (modalIsOpen) return;
alert("You hit 's'");
});
<!-- language: lang-html -->
<link href="//cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.3.2/css/bootstrap.css" rel="stylesheet"/>
<script src="//cdnjs.cloudflare.com/ajax/libs/jquery/2.1.3/jquery.js"></script>
<script src="//cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.3.2/js/bootstrap.js"></script>
<script src="http://cdn.rawgit.com/dmauro/Keypress/master/keypress.js"></script>
<!-- Button trigger modal -->
<button type="button" class="btn btn-primary btn-lg" data-toggle="modal" data-target="#myModal">
Launch demo modal
</button>
<!-- Modal -->
<div class="modal fade" id="myModal" tabindex="-1" role="dialog" aria-labelledby="myModalLabel" aria-hidden="true">
<div class="modal-dialog">
<div class="modal-content">
<div class="modal-header">
<button type="button" class="close" data-dismiss="modal" aria-label="Close">
<span aria-hidden="true">×</span>
</button>
<h4 class="modal-title" id="myModalLabel">Don't Act On Key Presses</h4>
</div>
<div class="modal-body">
Try Hitting S
</div>
</div>
</div>
</div>
<p>Try Hitting S</p>
<!-- end snippet -->